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  4. Jonas Warringer

Jonas Warringer

Senior Lecturer

Department of Chemistry & Molecular Biology
Mail
jonas.warringer@cmb.gu.se
Fax
+46 31-786 25 99
Visiting address
Medicinaregatan 7 B
41390 Göteborg
Room number
2301
Postal address
Box 462
40530 Göteborg

About Jonas Warringer

Cellular molecules, such as DNA, RNA, and proteins change across generations, creating heritable differences between cells and organisms and driving adaptation. Cancer, infection and resistance to chemotherapy and antibiotics are direct medical consequences of this molecular evolution. We combine the principles of evolutionary biology, population genetics and molecular and cellular biology to understand the rates and impacts of single nucleotide and copy number variations, the importance of neutral evolution vs. natural selection, the genetic nature of complex traits, and how changes to nuclear and organellar genomes influence aging, cancer and resistance to chemotherapy and antimicrobials. We often work with model microbes, such as the baker's yeast Saccharomyces cerevisiae, and the bacterium Escherichia coli, which is commonly found in the lower intestine of warm-blooded organisms. Our activities are at the interface between experimental and computational biology and use data from whole genome sequencing and automated measurements of cell growth, together with computational analysis and modelling and molecular and cellular biology techniques.